Our services

Mercachem is specialized in the following types of projects:

Discovery Chemistry

• Synthesis of building blocks and scaffolds
• Synthesis of reference standards and impurities
• Synthesis of metabolites (oxidation and conjugation)
• Synthesis of new chemical entities or analogs for hit-to-lead development
• Feasibility and validation studies towards parallel synthesis of libraries
• Parallel synthesis of focused libraries (10-1000 members)

Projects are carried out by employing the latest synthetic methodologies and equipment such as heterogeneous and homogeneous catalysis, biocatalysis and microwave chemistry, etc.

Medicinal Organic Chemistry

• Hit Optimization
• Hit to Lead
• Lead Optimization

Using a variety of optimization tools we can help you to select your candidate compounds.

Process R&D

• Production route development and scouting
• Small bulk supply (~1 kg, non-GMP)
• Catalyst screening and reaction optimization

Design of experiments, multivariate data analysis and parallel experimentation
are used as a tool to rapidly achieve reliable results.